(Wound Healing) The beneficial effect of S. nigra leaves in treating skin diseases
Wound healing potential of extract from Sambucus nigra L. leaves and its fractions.
Publication: Journal of Ethnopharmacology, Volume 320
Weronika Skowronska, Sebastian Grancia, Jakub P. Piwowarski, Lejsa Jakupovic, Marijana Zovko Koncic, Agnieszka Bazylko.
Abstract:
Ethnopharmacological relevance
Sambucus nigra L. (Viburnaceae), commonly known as black elderberry, is a native species throughout Europe and Western Asia. Elderberry leaves have been used in traditional European medicine, mainly externally, to treat skin and mucosal diseases. They are usually used as decoctions for washing hemorrhoids, ulcers, insect bites, wounds, scrapes, and gingivitis.
Results
The supportive effect of the elderberry leaves extract towards wound healing and modulation of the inflammatory response was demonstrated by induction of the keratinocytes. Additionally, the extract was shown to affect the cellular secretion of TNF-α and interleukins -1β, −6, and −8. Examinations of fractionated extract have shown that active principles were mainly contained in dichloromethane fraction. Eleven chemical constituents belonging to flavonoids, cyanogenic glycosides, and lignans were isolated and characterized.
Conclusion
The beneficial effect of S. nigra leaves in treating skin diseases has been partially verified and supports its traditional use in skin ailments of different etiologies.
Link to full article: https://www.sciencedirect.com/science/article/abs/pii/S037887412301293X?via%3Dihub